Drug choice for
osteoporosis of have to show ability protect and improve bone mass, taking care
of the quality of bone so that lessen bone risk broken, improve thicking of
bone or slow down speed of bone omission.
Drug choice for osteoporosis and
another bone disease include :
1. Derivate of
Bifosfonat.
Bifosfonat is one of
drug choice that can be recommended for osteopororsis because have function
prevent damage of bone, taking care of bone mass, and improve density of the
backbone and flank bone, and lessen bone risk broken.Derivate of Bifosfonat are
Risedronate, Alendronate, Pamidronate, Clodronate,Zoledronate, Ibandronate
acid.
2. Selective Estrogen
Receptor Modulator ( SERM ).
SERM can improve bone
mass but do not have negative effect of estrogen (giving of estrogen long-range
will increasing risk of ferocity at mammae anduterus ). Derivate of SERMS is
Raloxifene.
3. Metabolite of
vitamin D.
Metabolite of vitamin D
( calcitriol and alpha calcidol ) able lessen risk of bone broken as a effect
of osteoporosis.
4. Calcitonin.
Calcitonin be
recommended to be passed to one who suffer broken backbone accompanied pain.
Calcitonin can depress action of osteoclase and inhibit its expenditure.
5. Strontium ranelate.
Strontium Ranelate improve
forming of bone like precursor of osteoblas and making collagen, decreasing
resorption of bone through decreasing activity of osteoclase.
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