Bone consist of mineral such as phosphate and calcium, so
that bone became ossify and solid. If body unable to regulate mineral in bone,
will cause bone became more brittle and less solid, so that happened
osteoporosis.
Osteoporosis is bone disease that typically as a
mass of bone low, and be accompanied with quality of bone tissue that decrease
so that finally can generate brittleness of bone. Classification of
osteoporosis divided into two, primary osteoporosis often attack woman post
menopause and the man at old age, and secondary osteoporosis be caused disease
related to Cushing's disease, Hyperthyroidism, Hyperparathyroidism,
Hypogonadism, Abnormality of hepar , Failure of chronic renal, Less motion,
Habit drink alcohol, Use of drugs / corticosteroid, Excess of caffeine, and
Smoking.
Cause of osteoporosis is :
1. Osteoporosis of postmenopausal.
Occurring caused by want of estrogen as a main hormone at woman regulating the transportation of calcium into bone. Usually symptom appear at woman among 51-75 year, but can begin to emerge quicker or slower.
2. Osteoporosis of senilis
Possibility as a effect of want of calcium that related to age and imbalance among speed of bone destruction and forming of new bone. Senilis expressing this situation only happened at old age. This disease often happened at above age 70 year and 2 times a more regular attack woman. Woman oftentimes suffer osteoporosis of senilis and postmenopausal.
3. Osteoporosis of secondary.
Osteoporosis which be caused of failure chronic renal, abnormality of hormonal ( especially thyroid, parathyroid and adrenal ) and use of drugs ( for example corticosteroid, barbiturate, excess of tiroid hormone and anticonvulsant), drinking alcohol and smoking.
4. Osteoporosis of juvenile idiopathic.
Type of osteoporosis with cause unknown. This matter happened at young adult and children which have levels and function of hormone that normal, level of vitamin normal so that cause of brittleness of bone ill defined.
Factor risk osteoporosis :
1. Woman.
Osteoporosis often happened at woman that caused by estrogen which begin decrease its level in body since age 35 year. Besides, woman also experience menopause which can happened at age 45 year.
2. Age.
Along with accretion of age, function of body organ will decrease. At age 75-85 year, woman have risk 2 times fold if be compared to the man in experience loss of trabecular bone because process of aging, absorption of calcium decrease and the increase of function parathyroid.
3. Tribe.
Tribe also make difference white skin or clan ofasia
have biggest risk. This matter is caused generally consume calcium at asia
woman low, with one of reason is around 90% intolerance of lactose and avoid
product from animal. Dusky skin and hispanic have risk significant though
lower.
4. Clan of osteoporosis
If there is family member that suffering osteoporosis, will have opportunity to experience of osteoporosis. Osteoporosis attack patient with certain bone characteristic, such as equality posture and form of body bone. That its meaning in family line surely have structure of genetic bone that same.
5. Unfavourable Life Style
Consumption red flesh and also beverage have soda, because both containing phosphorus that stimulate forming of parathyroid hormone, as a cause release calcium from within blood. Beverage have caffeine and alcohol can generate bone that damage and brittle. Besides alcohol and caffeine as a toxin that inhibit form of bone mass ( osteoblas). Lazy of exercise will inhibit process of osteoblas, besides density of bone mass will decrease. Often doing exercise and motion can cause muscle will trigger bone to form mass. Smoker sensitive to osteoporosis, because nicotine can quicken absorption of bone, and also making activity and level of estrogen in body decrease so that weak bone cell formation in face of decay process. If calcium at body less hence body will release hormone to take calcium from part of other body, including exist in bone.
6. Consuming drugs.
Corticosteroid as a anti inflammatory can cause osteoporosis if often consumed in high dose will lessen bone mass because corticosteroid inhibit process of osteoblas. Besides, anticonvulsant and heparin also cause osteoporosis.
7. Posture of thin body.
Bone will active in forming cell if supported by ideal weight body. Because bone position support body hence bone will triggering to form mass at these area, especially at hip and flank. If thin body hence mass of bone forming become less perfectly.
Osteoporosis often conceived of silent disease because density of bone decrease slowly ( especially at osteoporosis of senilis ) and take place progressive during through years without be realized and without accompanied by the existence of symptom. Symptom newly appear at osteoporosis phase continue, such as broken bone, back which progressively bow, high of body decrease and the back pain.
To diagnose osteoporosis before the happening of broken bone can be done with inspection assessing density of bone, straightening diagnose of osteoporosis which often be done is :
1. DXA ( absorptiometry x-ray dual-energy ).
DXA very good for woman owning high risk suffer osteoporosis, patient with diagnose of osteoporosis not sure, and patient with result of medication have to be assessed in accurate figure.
2. Densitometer - Usg.
This inspection more precise as a screening early osteoporosis. Its result only marked with value of T where value more - 1 with the meaning that is density of bone good, value between - 1 and - 2,5 with the meaning osteopenia ( bone attenuating ), value less than - 2,5 with the meaning osteoporosis. The advantage of this inspection is practical and cheaper price.
3. Inspection of Ctx.
CTx is inspection of laboratory for the osteocalcin and dioksipiridinolin. Process osteoporosis can be known by checking biochemical sign of CTx ( C-Telopeptide). CTx represent result decomposition of bone collagen that release into circulating of blood so that specific in assessing speed process osteoporosis. Inspection of CTx also have the advantage in observation use medication oral antiresorpsi.
Principle of prevention for osteoporosis through maintaining or improving density of bone with consuming calcium that enough, doing sport like walking and taking a ride doorstep, giving derivate of selective estrogen receptor modulator that be recommended like Raloxifene because have not effect of mammae and uterus.
Cause of osteoporosis is :
1. Osteoporosis of postmenopausal.
Occurring caused by want of estrogen as a main hormone at woman regulating the transportation of calcium into bone. Usually symptom appear at woman among 51-75 year, but can begin to emerge quicker or slower.
2. Osteoporosis of senilis
Possibility as a effect of want of calcium that related to age and imbalance among speed of bone destruction and forming of new bone. Senilis expressing this situation only happened at old age. This disease often happened at above age 70 year and 2 times a more regular attack woman. Woman oftentimes suffer osteoporosis of senilis and postmenopausal.
3. Osteoporosis of secondary.
Osteoporosis which be caused of failure chronic renal, abnormality of hormonal ( especially thyroid, parathyroid and adrenal ) and use of drugs ( for example corticosteroid, barbiturate, excess of tiroid hormone and anticonvulsant), drinking alcohol and smoking.
4. Osteoporosis of juvenile idiopathic.
Type of osteoporosis with cause unknown. This matter happened at young adult and children which have levels and function of hormone that normal, level of vitamin normal so that cause of brittleness of bone ill defined.
Factor risk osteoporosis :
1. Woman.
Osteoporosis often happened at woman that caused by estrogen which begin decrease its level in body since age 35 year. Besides, woman also experience menopause which can happened at age 45 year.
2. Age.
Along with accretion of age, function of body organ will decrease. At age 75-85 year, woman have risk 2 times fold if be compared to the man in experience loss of trabecular bone because process of aging, absorption of calcium decrease and the increase of function parathyroid.
3. Tribe.
Tribe also make difference white skin or clan of
4. Clan of osteoporosis
If there is family member that suffering osteoporosis, will have opportunity to experience of osteoporosis. Osteoporosis attack patient with certain bone characteristic, such as equality posture and form of body bone. That its meaning in family line surely have structure of genetic bone that same.
5. Unfavourable Life Style
Consumption red flesh and also beverage have soda, because both containing phosphorus that stimulate forming of parathyroid hormone, as a cause release calcium from within blood. Beverage have caffeine and alcohol can generate bone that damage and brittle. Besides alcohol and caffeine as a toxin that inhibit form of bone mass ( osteoblas). Lazy of exercise will inhibit process of osteoblas, besides density of bone mass will decrease. Often doing exercise and motion can cause muscle will trigger bone to form mass. Smoker sensitive to osteoporosis, because nicotine can quicken absorption of bone, and also making activity and level of estrogen in body decrease so that weak bone cell formation in face of decay process. If calcium at body less hence body will release hormone to take calcium from part of other body, including exist in bone.
6. Consuming drugs.
Corticosteroid as a anti inflammatory can cause osteoporosis if often consumed in high dose will lessen bone mass because corticosteroid inhibit process of osteoblas. Besides, anticonvulsant and heparin also cause osteoporosis.
7. Posture of thin body.
Bone will active in forming cell if supported by ideal weight body. Because bone position support body hence bone will triggering to form mass at these area, especially at hip and flank. If thin body hence mass of bone forming become less perfectly.
Osteoporosis often conceived of silent disease because density of bone decrease slowly ( especially at osteoporosis of senilis ) and take place progressive during through years without be realized and without accompanied by the existence of symptom. Symptom newly appear at osteoporosis phase continue, such as broken bone, back which progressively bow, high of body decrease and the back pain.
To diagnose osteoporosis before the happening of broken bone can be done with inspection assessing density of bone, straightening diagnose of osteoporosis which often be done is :
1. DXA ( absorptiometry x-ray dual-energy ).
DXA very good for woman owning high risk suffer osteoporosis, patient with diagnose of osteoporosis not sure, and patient with result of medication have to be assessed in accurate figure.
2. Densitometer - Usg.
This inspection more precise as a screening early osteoporosis. Its result only marked with value of T where value more - 1 with the meaning that is density of bone good, value between - 1 and - 2,5 with the meaning osteopenia ( bone attenuating ), value less than - 2,5 with the meaning osteoporosis. The advantage of this inspection is practical and cheaper price.
3. Inspection of Ctx.
CTx is inspection of laboratory for the osteocalcin and dioksipiridinolin. Process osteoporosis can be known by checking biochemical sign of CTx ( C-Telopeptide). CTx represent result decomposition of bone collagen that release into circulating of blood so that specific in assessing speed process osteoporosis. Inspection of CTx also have the advantage in observation use medication oral antiresorpsi.
Principle of prevention for osteoporosis through maintaining or improving density of bone with consuming calcium that enough, doing sport like walking and taking a ride doorstep, giving derivate of selective estrogen receptor modulator that be recommended like Raloxifene because have not effect of mammae and uterus.
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